NuvaRing® (etonogestrel/ethinyl estradiol vaginal ring) Is Easy to Use

Inserting NuvaRing

Choose an insertion position that is most comfortable for you.
  • For example, lying down, squatting, or standing with one leg up. (See figure below.)
Insertion Diagram for NuvaRing® (etonogestrel/ethinyl estradiol vaginal ring)
Open the pouch to remove your NuvaRing.
  • Each NuvaRing comes in a re-sealable foil pouch.
  • Wash and dry your hands before removing NuvaRing from the foil pouch.
  • Open the foil pouch at either notch near the top.
  • Keep the foil pouch so you can place your used NuvaRing in it before you throw it away in your household trash.

Insertion of NuvaRing® (etonogestrel/ethinyl estradiol vaginal ring) Prepare for NuvaRing insertion. Hold NuvaRing between your thumb and index finger and press the sides of the ring together. (See figure to the right.) Insert NuvaRing into your vagina. How to Insert NuvaRing® (etonogestrel/ethinyl estradiol vaginal ring) Insert NuvaRing into your vagina. Insert the folded NuvaRing into your vagina and gently push it further up into your vagina using your index finger. (See figure to the left.) Alternatively, the applicator for NuvaRing (available separately) may be used to help you insert the ring. See NuvaRing Instructions for Use. When you insert NuvaRing it may be in different positions in your vagina, but NuvaRing does not have to be in an exact position for it to work. NuvaRing may move around slightly within your vagina. This is normal. Although some women may be aware of NuvaRing in the vagina, most women do not feel it when it is in place.

  • If the NuvaRing feels uncomfortable, you may not have pushed the ring into your vagina far enough. Use your finger to gently push the NuvaRing as far as you can into your vagina. Rest assured that once inserted into the vagina, there is no danger of NuvaRing being pushed too far up or getting lost.
  • Some women have accidentally inserted NuvaRing into their bladder. If you have pain during or after insertion and you cannot find NuvaRing in your vagina, call your health care provider right away.

Important Safety Information
Do not use NuvaRing if you smoke cigarettes and are over age 35. Smoking increases your risk of serious heart and blood vessel problems from combination hormonal contraceptives (CHCs) including heart attack, blood clots, or stroke which can be fatal. This risk increases with age and the number of cigarettes smoked.
  • The use of a CHC, like NuvaRing, is associated with increased risks of several serious side effects, including blood clots, stroke, or heart attack. NuvaRing is not for women with a history of these conditions or any condition that makes your blood more likely to clot. The risk of getting blood clots may be greater with the type of progestin in NuvaRing than with some other progestins in certain low-dose birth control pills. The risk of blood clots is highest when you first start using CHCs and when you restart the same or different CHC after not using it for a month or more.  
  • NuvaRing is also not for women with high blood pressure that medicine can’t control; diabetes with kidney, eye, nerve, or blood vessel damage; certain kinds of severe migraine headaches; liver disease or liver tumors; take any Hepatitis C drug combination containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir, as this may increase levels of the liver enzyme “alanine aminotransferase” (ALT) in the blood; unexplained vaginal bleeding; breast cancer or any cancer that is sensitive to female hormones; or if you are or may be pregnant.
  • NuvaRing does not protect against HIV infection (AIDS) and other sexually transmitted infections.
  • The most common side effects reported by users of NuvaRing are irritation inside your vagina or on your cervix; headache (including migraine); mood changes (including depression); the ring slipping out or causing discomfort; nausea and vomiting; vaginal discharge; weight gain; vaginal discomfort; breast pain, discomfort, or tenderness; painful menstrual periods; abdominal pain; acne; and less sexual desire.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

Please read the Patient Information for NuvaRing (etonogestrel/ethinyl estradiol vaginal ring), including the information about the increased risk of serious cardiovascular side effects, especially in women who smoke, and discuss it with your health care provider. The physician Prescribing Information also is available.